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4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine

Product Code

TRC-A603004-5MG

CAS Number

221243-82-9

Product Format

Neat

Matrix

-

Molecular Formula

C19 H19 N5

Molecular Weight

317.39

Pack Size:

5 mg

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Product Information

A potent and uniquely specific tyrosine kinase inhibitor of an engineered v-Src tyrosine kinase. A selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl which preferentially inhibits mutant over wild-type knases. 

 

References
[1] Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999) [2] Davies, S., et al.: Biochem. J., 351, 95 (2000) [3] Regan, J., et al.: J. Med. Chem., 45, 2994 (2002) [4] Bain, J., et al.: Biochem. J., 371, 199 (2003) [5] Kuma, Y., et al.: J. Biol. Chem., 280, 19472 (2005)

CAS Number

221243-82-9

Molecular Formula

C19 H19 N5

Molecular Weight

317.39

Accurate Mass

317.164

Smiles

CC(C)(C)n1nc(c2cccc3ccccc23)c4c(N)ncnc14

InChI

InChI=1S/C19H19N5/c1-19(2,3)24-18-15(17(20)21-11-22-18)16(23-24)14-10-6-8-12-7-4-5-9-13(12)14/h4-11H,1-3H3,(H2,20,21,22)

IUPAC

1-tert-butyl-3-naphthalen-1-ylpyrazolo[3,4-d]pyrimidin-4-amine

Storage Temperature

-20C Freezer

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Matrix

-

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